Research
Our Research Efforts
PAAZ continues to actively research and pursue the integration of psilocybin and other psychedelics into mental health care.
Our Research Efforts
PAAZ continues to actively research and pursue the integration of psilocybin and other psychedelics into mental health care. The links to studies and articles found below focus on understanding the therapeutic potential of these substances in treating various mental health conditions such as depression, PTSD, and anxiety. Visit this page often to stay informed and up to date on efforts being made to change the landscape of mental health treatment and the options that are available to Arizonans.
Research Studies
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- May 7, 2025
The New England Journal of Medicine
Trial of Psilocybin versus Escitalopram for Depression
Read the full studyPsilocybin may have antidepressant properties, but direct comparisons between psilocybin and established treatments for depression are lacking.
- May 7, 2025
eClinicalMedicine
Single-dose psilocybin-assisted therapy in major depressive disorder: a placebo-controlled, double-blind, randomised clinical trial
Read the full studyPsilocybin has been suggested as a novel, rapid-acting treatment for depression. Two consecutive doses have been shown to markedly decrease…
- May 7, 2025
National Library of Medicine
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial
Read the full studyCancer patients often develop chronic, clinically significant symptoms of depression and anxiety. Previous studies suggest that psilocybin may decrease depression…
- May 7, 2025
International Journal of Drug Policy
Psychedelic use is associated with reduced daily opioid use among people who use illicit drugs in a Canadian setting
Read the full studyResearch into the therapeutic and naturalistic uses of psychedelics for improving outcomes related to mental health disorders has generated increasing…
- May 7, 2025
Frontiers in Psychiatry
Naturalistic psilocybin use is associated with persisting improvements in mental health and wellbeing: results from a prospective, longitudinal survey
Read the full studyThe classic psychedelic psilocybin, found in some mushroom species, has received renewed interest in clinical research, showing potential mental health…
- May 7, 2025
npj Mental Health Research
The effect of psilocybin on empathy and prosocial behavior: a proposed mechanism for enduring antidepressant effects
Read the full studyPsilocybin is a serotonergic psychedelic shown to have enduring antidepressant effects. Currently, the mechanism for its enduring effects is not…
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